University of Wisconsin–Madison

2026 International Ultrasonics Symposium Challenge

October 4-8, 2026 | Raleigh, North Carolina, USA

Pulse-echo quantitative ultrasound (QUS) is a well-established research field. Studies have demonstrated the diagnostic values of QUS features in a wide range of clinical and preclinical applications. In the past ten years, major medical ultrasound companies have introduced commercial implementations of QUS features motivated by their potential as indicators of fatty liver disease.

Despite the increasing interest in QUS, important challenges remain, most importantly the need to compensate for the effects of intervening tissues between the transducer and the tissue of interest. To address these challenges, novel QUS methods have been investigated to improve the compensation for total attenuation along the acoustic path and to reduce the effects of aberration through estimation of the speed of sound.

Numerous algorithms and methods exist, and the time has come to compare and evaluate them in a rigorous matter. The proposed challenge will provide (i) a wide platform to bring together research efforts from laboratories across the globe and (ii) a framework to compare the QUS algorithms developed by these laboratories in a uniform and standardized manner. Based on ultrasound data generated from realistic simulations and acquired from phantoms with known acoustical properties, participants will compete to develop the most accurate and precise methods (in terms of bias and variance) and with the best lesion detectability. 

Overall Goal: Provide a uniform framework to compare the performance of different attenuation and speed of sound estimation algorithms over a wide range of expected values. 

  • Specific objective 1: Identify the algorithms that provide the most accurate and precise estimates of the attenuation coefficient and speed of sound over a wide range of conditions using radio-frequency (RF) data from computational and experimental phantoms.  
  • Specific objective 2: Identify the algorithms that provide the best lesion detectability, i.e., able to detect the smallest spatial variation of attenuation or speed of sound.  
  • Specific objective 3: Identify the algorithms that provide the most robust estimates of attenuation and speed of sound to the presence of near-field aberration.  

ORGANIZERS

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Cameron

Cameron Hoerig, PhD

Instructor of Biomedical Engineering in Radiology

Department of Radiology

Weill-Cornell School Medicine

Aiguo

Aiguo Han, PhD

Assistant Professor

Biomedical Engineering and Mechanics

Virginia Tech

Ivan

Ivan Rosado-Mendez, PhD

Assistant Professor

Departments of Medical Physics and Radiology

University of Wisconsin-Madison

Jonathan

Jonathan Mamou, PhD

Professor

Department of Radiology

Weill-Cornell Medicine

Jonathan

Jonathan Hale, MSc

University of Wisconsin – Madison

Zixhuan

Zixhuan Tian, PhD

Virginia Tech

Cristel

Cristel Baiu, MSc

University of Wisconsin-Madison

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